Innovative microscope discloses full 3D molecular orientation in cells

Innovative microscope discloses full 3D molecular orientation in cells

/ Biology / By


Polarized dispim microscope, which can create an image of full 3D orientation and molecules in cells. The device was built at Hari Shroff Lab at the National Institute of Biomedical Imaging and Bio -Engineering (NIBIB), when the idea was conceived in Marine Biological Laboratory, Woods Hole. The liquid crystal used for polarized lights is shown in green circle. The dual view of the dispim is found at a right angle on the path sample. See Chandler et al., PNAS, 2025. Credit: Min Guo







Reborning a plant cell (zilem) with its cellulose fiber with red (left) labeled. Center reconstruction refers to the orientation of each cellulose fiber, which contains orientation indicated by color. On the right is the image from the microscope. The cell was imaged with a polarized dual visual lightheet microscope (polarized dispim). See Chandler et al., PNAS, 2025. Credit: Chandler et al., owner2025.

A confluence of vision

Citation: Innovative microscope reveals complete 3D molecular orientation in cells (2025, 22 February) on 22 February 2025 https://pheys.org/news/news/2025-02-02- taken from .html

This document is subject to copyright. In addition to any impartial behavior for the purpose of private studies or research, no part can be re -introduced without written permission. The content is provided for information purposes only.

(Tagstotransite) Science (T) Physics News (T) Science News (T) Technology News (T) Physics (T) Material (T) Nanotech (T) Technology (T) Science

Must Read