Often giving blood can make your blood cells healthy

Repeated blood donors may get more than a warm, fuzzy spirit than their philanthropicness, as blood can also increase your ability to produce healthy blood cells, possibly reduce the risk of blood cancer growth.

Hector Herga Enkabo At the Francis Crick Institute in London and his colleagues analyzed genetic data extracted from blood cells donated by 217 men in Germany, which were between 60 and 72, who gave blood more than 100 times. He also saw the samples of 212 men of the same age, who had donated less than 10 times, and found that often the donors were more likely to carry some mutations in a gene to blood cells. Dnmt3a,

To understand this difference, the team genetically engineers human blood stem cells – which give birth to all blood cells in the body – with these mutations and added them to the lab dish with unmarried cells. To mimic the effects of blood donation, he also added a hormone called EPO, which produces the body after loss of blood, in some dishes.

A month later, consistent-dotation cells increased 50 percent faster than those without mutation, but only in ePO dishes. Without this hormone, both cell types grow at a similar rate.

“It suggests that every blood donation, you are going to burst the EPO in your system and it is in favor of the development of cells with them. Dnmt3a Mutation, ”says Enkabo.

To check if it is beneficial to exceed these mutated blood cells, the team mixed them with the cells carrying mutations that increase the risk of leukemia, and again found that, in the presence of EPOs, in the presence of EPOs, continuously-two-cells defeated others to a great extent, and were better to produce red blood cells. this shows that Dnmt3a Mutations are beneficial and can suppress the growth of cancer cells, says INkabo.

“It is such that blood donation is providing a selection pressure to increase your fitness of stem cells and increase their ability to re -fill,” Ash Toy At Bristol University, Britain. “Not only can you save someone’s life, but perhaps you are increasing the fitness of your blood system.”

This requires further work to verify whether it is really the case, says Mark Mansoor University College London, as laboratory experiment in the body provides a highly simplified picture of what happens in the body. “It needs to be valid in a very large cohort, in various ethnicities in women and other age groups,” says Mansoor. He also states that without donors Dnmt3a Mutation cannot see this benefit.