Recent outbreaks of highly pathogenic avian influenza (also known as bird flu) have created a need for rapid and sensitive identification methods to reduce its spread. Now, Researcher in ACS sensor A prototype sensor is developed that detects a type of influenza virus that causes bird flu (H5N1) in air samples. The low -cost handheld sensor detects the virus at the level below an infectious dose and can conduct rapid aerosol tests for Airborne avian influenza.
Bird flu may spread quickly when infectious respiratory drops are breathed by birds and other animals, and frequent mutations of virus make air transmission a concern for humans. Current methods often require extensive sample preparations in a laboratory to detect the H5N1 virus, such as the polymerase chain reaction (PCR)-in-the-end tests. Therefore, a sensor that quickly detects these airborne viral particles can identify transmission before a sample preparation. A solution can be an electrochemical capacitive biosensor (ECB), which has been used to successfully detect other aerial virus. Earlier, a research team led by Rajan Chakraborty An electrochemical biosensor made to detect sars-cov-2 particles in the breathThis time, the team instead used ECB technology to detect and measure the level of H5N1 virus in the air.
The new ECB consists of a thin network of prizes blue nanocristal and graphine oxide branches on screen-crushed carbon electrodes. To detect the H5N1 virus to the sensor, the researchers attached a sensitive examination of these pathogens on the network. They paired the sensor with a custom-made air sample that draws into drops from the air and forms a liquid sample. When the liquid samples with the H5N1 virus were applied to the sensor, the viral particles tied the tied and changed the sensor. By measuring the total changes in the tuberculosis, researchers can measure the level of H5N1 in liquid samples.
In demonstrations with aerosolized samples with known volume of inactive H5N1 virus, ECB created results within 5 minutes. The detection level of the sensor for avian influenza was 93 viral copy per 35 cubic feet (1 cubic meter) in the air, a level that researchers say that “be sufficient sensitive to detect the presence of H5N1 under the infectious dose of the virus.” The overall accuracy of the sensor was more than 90% compared to a digital PCR test, the measurement by the traditional method. Chakraborty and the team say that the new bird flu sensor shows the promise for real-time air monitoring, non-time for both animal and human population.
The author accepts funding from Flu Lab.
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