Q&A: Can self-drawing lab lead to a new era of scientific research?

Q&A: Can self-drawing lab lead to a new era of scientific research?


Credit: Milad Ebolasani

An interdisciplinary team of scientists and engineers argues that the research community should make a concrete effort to redeem the advances in robotics and artificial intelligence (AI), which addresses permanent energy, emerging diseases and other global challenges.

“Self-Driving Labs (SDL) will serve as partners for human researchers, significantly reduce the time and cost required to reach scientific solutions,” Milad Ebolasani, an expert in the region and Alcoa Professor Millad Abolsani of Chemical and Biomolecular Engineering at Northern Carolina State University.

“They will not replace the unique expertise or creativity of human researchers. Instead, these advanced technologies will streamlive tired and repetitive experimental functions, automate data analysis, and help in informed decision making. This approach enables researchers to rapidly detect new ideas, carry forward innovation and speed up innovation.”

Abolhasani and a dozen colleagues published a piece In Nature communication On April 24, creating a blueprint for how SDLs can accelerate valuable research – and how a new approach to these devices can make technology more accessible and accelerate research in important areas.

We talked to Abolhasani about the argument that he and his colleague are making in favor of SDL, and what the path ahead could see further.

What is a self-driving lab?

An SDL is essentially a robot co-pilot for scientific research. This automatically automatically enters the scientific research process – from designing and executing them to analyze the results. Equipped with AI, robotics and automation, SDL learns dynamically and optimize based on experimental results, continuously improve its methods through a closed loop process. Think of it as an AI-powered robotic collaborator that helps scientists to detect new ideas, to streamline research workflows and accelerate groundbreaking discoveries.

What is the big idea of ​​you and your colleagues in this paper?

In our recent article, Published In Nature communicationWe discuss the huge potential of SDL (12 other SDL researchers from 11 institutions in the United States and Europe and I) to streamlinom science and accelerate scientific discoveries globally.

We throw light on how SDL can dramatically increase cooperation and innovation in various scientific subjects. Additionally, we address the existing obstacles to make this vision a reality and propose strategic solutions including centralized SDL features and a coordinated effort between distributed laboratory networks. To achieve this ambitious goal, we emphasize the need to prioritize federal and industrial investments along with educational research targeted for building reliable, accessible and strong SDL infrastructure.

Can you give me examples of real -world problems or scientific progress that SDL has already addressed? Or do you face challenges that self-driving labs are exceptionally well suited?

SDL has already demonstrated significant cuts in time and cost required to get solutions in important areas such as energy, environment and health care. For example, SDL has accelerated research successes in battery technologies, solar cell development, pharmaceuticals, special materials and wearable electronics, which achieves 10 to 100 times faster than traditional methods.

With further progress, SDL has the ability to accelerate research 1,000 times, making them exceptionally well suited to deal with complex, multidimensional problems that include comprehensive experiments.

Q&A: Can self-drawing lab lead to a new era of scientific research?

A planned observation of how a self-driving laboratory (SDL) operates. Credit: Nature communication (2025). Doi: 10.1038/s41467-025-59231-1

Okay, let me back for a second. Broadly, what benefits can SDL provide for the research community? Why would researchers like to use these techniques?

Researchers are rapidly turning to SDL, as robot colleagues are capable of navigating high-dimensional experimental locations with extraordinary efficiency. SDLs enable rapid hypothesis tests, recurrence of experimental strategies and intelligent exploration of complex parameter landscapes. These systems accelerate research process, reduce experimental costs and reduce human error by automating labor-intensive and repetitive functions. By closing these burdens, SDL allows researchers to focus on scientific questions and creativity, which facilitate modern, cloud-connected team science on an unprecedented speed and scale.

You and your associates talk about a coordinated effort consisting of both centralized research facilities and a distributed network of laboratories that work separately. What is the benefit of this approach?

The combination of centralized SDL features with distributed laboratories ensures both high-demonstration capabilities and broader access. Centralized SDLs can handle complex, resource-intensive research, while distributed laboratories offer ease in flexibility and access, allowing scientists to actively participate in state-of-the-art research everywhere.

Why is this important? And why are you and your colleagues now putting this idea forward?

A coordinated effort is important for both centralized and distributed SDL because current global challenges – such as energy lack, rapid emerging diseases and immediate environmental crisis – require solutions within months rather than decades. Fast-track scientific solutions are important, and SDLs are specificly deployed to meet this immediate requirement. We are now proposing this concrete effort as recent successes in AI, robotics and lab automation have achieved it technically, while facing global challenges, which is necessary to deploy these advanced abilities immediately.

What are the most important challenges to proceed with this vision of science acceleration with SDL and access?

Major challenges include ensuring reliable hardware and technology integration, which means creating strong, interopeable systems that can continuously perform complex experimental workflows with minimal downtime and high precision. Spontaneous integration of software and hardware components is necessary to support adaptive automation and copy abilities in various research applications.

Another basic requirement is the generation and management of large versions of high quality data. The AI ​​models running SDL rely more on these figures for training, prediction and continuous improvement. Without rigid data quality standards and coherent metadata practices, the reliability and generality of SDL output is compromised.

Q&A: Can self-drawing lab lead to a new era of scientific research?

The cycle of challenges challenging the advancement of self-driving laboratory (SDL) technologies. Credit: Nature communication (2025). Doi: 10.1038/s41467-025-59231-1

Additional challenges include establishing standard for transfer and growth. It refers to shared protocols, format, and oncology creating that allow insight, experimental strategies, and allow the model learned from an SDL to easily move, reuse or manufacture by others. Such standard will ensure easy cooperation and integration in different platforms and subjects, which will make it possible for SDL to increase each other’s capabilities and accelerate team science.

Additionally, it is necessary to develop a skilled workforce capable of designing, maintaining and operating these refined platforms. The current SDL landscape is fragmented, focusing on app-specific hardware and software with several attempts. In fact, scalable, associate team requires a concrete change in the direction of developing application-unknown SDL systems, which can serve as flexible, inter-platforms in many subjects.

Finally, legal and safety standards should be considered careful to ensure responsible deployment and long -term stability of SDL technologies.

Can you explain more about legal and safety standards?

Legal and safety standard refers to policies, certificates and best practices to ensure that SDL works within the regulatory structure while maintaining laboratory safety and compliance. This includes safe handling of dangerous materials, traced data practices, responsible use of AI and clear guidelines for intellectual property rights. Establishing these standards is necessary to create confidence in SDL technologies and enable their wider and responsible adoption.

So, what are the next stages? Where do you start?

The next stages include strategic, large -scale participation between education, industry and government agencies, align efforts, establish universal standards and to include safe funds for reliable SDL infrastructure. Industry participation should include both the equipment manufacturer of SDL technologies and the final user. Additionally, the initial pilot programs and dedicated Testbands demonstrate the effectiveness of centralized and distributed SDL models, which will be important and refined to both centralized and distributed SDLs.

If everything goes completely, then how do you see it playing in the next 10 years?

In an ideal scenario, SDL will become a mainstream associate within the next decade-a robotic co-pilot-for researchers around the world, basically we see the way we look at the approach to scientific research. They will rapidly run innovation, increase global scientific cooperation and dramatically intensify successes, which will make it possible to solve complex and immediate global challenges in areas such as environmental stability, energy efficiency and personal health care.

The paper was co-author in NC State by postdorel researchers, Richard Cantty and Jeffrey Bennett; Martin Sefrid, Assistant Professor of Material Science and Engineering in NC State; Keith Brown of Boston University; Tonio Bounasi of MIT; Sergei Kalinin of Tennessi University; John Kichin of Carnegie Melan University; Air Force Research Laboratory Benji Maruyama; Oak Ridge National Laboratory Robert Moore; Joshua Shire of Fordham University; Shijing Sun of the University of Washington; And Tejaz Veg of Technical University of Denmark.

More information:
Richard b. Cantty et al, science acceleration and access with self-driving laboratories, Nature communication (2025). Doi: 10.1038/s41467-025-59231-1

Granted by Northern Carolina State University


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